To ensure safety, Wei says the current test vaccine uses HER2 genes that are altered so that they are not oncogenic. Contain contain produced no 'intracellular domain ' - the part of the receptor just below just below the cell surface, and transmits the signals to the nucleus growth. The first vaccine was also safe, she says, but contained a little more of the native HER2 receptor structure. 'With this vaccine, I am quite sure that the receptor is functionally 'm dead,'she said. 'The greatest power of vaccination against early development of cancer, and that is our ultimate goal with this treatment,'Wei said.
HER2 receptors promote normal cell growth, and is found in small amounts in normal breast cells. But HER2-positive breast cancer cells contain many more receptors than normal, promoting a particularly aggressive type of tumor that 20 to 30 % of all patients are affected with breast cancer. Therapies such as trastuzumab and lapatinib, designed to, latch on to these receptors and destroy them.
The study, from the September Cancer Research, Cancer Research, a journal of the American Association for Cancer Research reports suggests the vaccine could. Women with HER2-positive, treatment-resistant cancer treatment or prevention of cancer recurrence The researchers also say that it could potentially be used in cancer - free women initial development initial development of these tumors..This draft standards / draft guidance are available Internet on the NICE site of Tuesday, June to 17.00 clock on Tuesday, July. Standards that enables registered participants comment and help to identify which of the claims and recommend have the most important to support service improvement -. All eligible opinions of the Guidance Development Group and of the standards of / guidelines will be reviewed can be refined the light of these More Information. To final quality of standards and guidelines are to be published in October 2014.
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NICE which opens today also consultation on two preliminaries pieces on clinical guidelines on service users User in adult learning mental health and improving quality patient care User. Those management is of the first time, on Tuesday in addition to standards of quality designed and aims at men based care, consideration of service user and patient will needs, concerns and desires to promote.