ADRB receptors play a direct function in Src activation by PKA-mediated mechanism Scientists at The University of Texas MD Anderson Malignancy Center can see the signaling pathway whereby a grasp regulator of cancers cell proteins - known as Src - potential clients to ovarian cancers progression when subjected to tension hormones. The researchers record in the current issue of Character Communications that beta blocker medicines mitigate this effect and reduce malignancy deaths by typically 17 %. Src is usually a proto-oncogene - a standard gene that can become an oncogene due to increased expression - involved in the regulation of cell development and division. Known to be instrumental to changes that cause regular cells to go awry, this study sheds light on its functional role as an integral molecular switch impacting a downstream signaling pathway that spurs disease progression.and A*STAR's Experimental Therapeutics Centre today announced the release of a drug screening platform within ETC's new Singapore Screening Centre. This partnership provides a full spectrum of state-of-the-art automation systems to biomedical researchers, enabling highly efficient drug screening in one location. The Singapore Screening Centre conducts high-throughput screening to recognize potential drug applicants against disease, using a library of over 300,000 chemical substances. It today employs Agilent's dual BioCel 1200 integrated program, which automates and coordinates the various processes of high-throughput screening, including compound management, assay plate preparation and experiment replication, to ensure high-quality data while conserving time and reducing the possibility of human mistake.