There was no significant difference in the geometric mean peak titers based on the malaria exposure index . As previously described,4 we found a nonlinear association between the imputed anti-circumsporozoite antibody titer and security from clinical malaria whenever we included data from the full 4-season follow-up period . Discussion During 4 years of follow-up, RTS,S/AS01E was associated with 29.9 percent and 16.8 percent efficacy against first and all episodes of P. Falciparum clinical malaria, respectively, among children vaccinated at 5 to 17 months old in a national nation where malaria is endemic. The efficacy estimate during follow-up is encircled by significant uncertainty.'A test that may not just diagnose the disease in individuals showing telltale symptoms, but perhaps also detect the condition years before these symptoms show up would make early therapeutic intervention possible. This would be a significant breakthrough as pharmaceutical companies are now working feverishly to develop new drugs that may stop or gradual the progression of Alzheimer's.' Related StoriesResearchers successfully repair nerve cell damage in Alzheimer's dementiaStudy reveals mechanism behind protein-related diseasesEight myths and truths about Alzheimer's diseaseAn expense in Durin Systems, Inc., by Foundation Venture Capital Group , LLC, a fresh Jersey Health Foundation affiliate marketer that invests in start-up companies founded by researchers at UMDNJ, provided required funding to go Nagele's research ahead.