The establishment of a comparative effectiveness research center may ultimately improve treatment outcomes. Nevertheless, the principal concern of some individuals is whether it will evolve right into a gatekeeper for reimbursement and/or rationing ultimately, and ultimately hamper the margins and R&D attempts of innovators . The special record, 'U.S. Health care Sector Legislative and Regulatory Register - Fall 2009' is currently offered by.. Affordable HEALTHCARE Act to improve number of insured Us citizens by 36 million According to Fitch Ratings' Fall U.S.Than reopen enrollment in the initial trial Rather, we achieved the targeted enrollment by amending the protocol to prospectively combine the sample in the original trial with the sample in the ongoing trial . The latter was a substudy of the initial trial and was conducted in China, Taiwan, and South Korea . Because an analysis of pooled data from these trials was likely to be carried out for regional regulatory and reimbursement purposes, the trials were identical with regard to patient-selection style and criteria, except that health-related standard of living and medical source utilization weren't assessed in the substudy.