The researchers found that total OAS scores were significantly higher in BD II patients than controls, at 15.0 versus 2.5, as were ratings for all three OAS sub-items, at 10.5 versus 0.6 for aggression, 3.5 versus 1.8 for irritability, and 1.0 versus 0 for suicidality. There have been no significant differences in SERT availability between BD II individuals and controls in the midbrain, the thalamus, or the striatum. However, there is a significant correlation between SERT availability in the midbrain and total OAS score, as well as all OAS sub-item ratings, in BD II patients. There is no such association in controls, no associations between SERT availability and OAS scores in other brain regions in either BD II sufferers or handles. Chou and group conclude in the Journal of Affective Disorders: The bigger total scores of OAS in euthymic BD II patients than in HCs [healthful controls] support the idea that aggression might be a trait marker for BD.Wachter interviewed three former national coordinators for health information technology : the libertarian-inclined David Brailer, who provides such faith in market-driven technology that he believed in the organization he was leading hardly; David Blumenthal, the consummate diplomat, whose $30 billion budget was 71,000 percent greater than Brailer's and who, in precipitating widespread adoption, was the most successful leader arguably; and Farzad Mostashari, the most controversial perhaps, whose hard-line insistence on the need for Meaningful Make use of 2 provides been widely criticized. Wachter provides sympathetic airing to each but is unsparing about the overreach of MU requirements . So why concentrate on meaningful make use of than interoperability rather? Some generous explanations: As Blumenthal notes, there can be no interoperability without operability.