Symptoms may include fever, chills, and flank discomfort, which identifies pain in the lower back. Kidney stones. Symptoms may include serious abdominal or pelvic discomfort. Urinary tract infections. Urinary tract infections frequently occur when bacteria enter your body through the urethra and begin to multiply in your bladder. Symptoms range from a persistent urge to urinate, discomfort and burning with urination, and strong-smelling urine extremely. Enlarged prostate. The prostate gland - - located just below the bladder and surrounding the top portion of the urethra - - frequently begins growing as guys approach middle age.In the current research, we observed three situations in which the absolute neutrophil count decreased to less than 1500 per cubic millimeter and a dose-dependent upsurge in both LDL and HDL cholesterol concentrations however, not an increase in aspartate aminotransferase, alanine aminotransferase, or serum creatinine concentrations or a decrease in serum hemoglobin concentration. The mechanism for the alterations in cholesterol profile is usually unknown. The clinical consequences of these laboratory abnormalities require additional study.